BRD-K86856088_UNC0638_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K86856088_UNC0638_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CALML5 calmodulin-like 5
CCDC92 coiled-coil domain containing 92
CLU clusterin
DHCR7 7-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
EGR3 early growth response 3
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FOLR1 folate receptor 1 (adult)
GSE1 Gse1 coiled-coil protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
JMJD6 jumonji domain containing 6
KDM5A lysine (K)-specific demethylase 5A
KLF9 Kruppel-like factor 9
MARCKS myristoylated alanine-rich protein kinase C substrate
MMD monocyte to macrophage differentiation-associated
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NNMT nicotinamide N-methyltransferase
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OBSL1 obscurin-like 1
OXA1L oxidase (cytochrome c) assembly 1-like
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRKCI protein kinase C, iota
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
TAGLN2 transgelin 2
TUBB2B tubulin, beta 2B class IIb
TXNIP thioredoxin interacting protein
UNC13B unc-13 homolog B (C. elegans)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AQP3 aquaporin 3 (Gill blood group)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CFH complement factor H
CLEC2B C-type lectin domain family 2, member B
DIO1 deiodinase, iodothyronine, type I
ESR1 estrogen receptor 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FRZB frizzled-related protein
FXYD3 FXYD domain containing ion transport regulator 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
H2AFV H2A histone family, member V
HBE1 hemoglobin, epsilon 1
HOPX HOP homeobox
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IFI16 interferon, gamma-inducible protein 16
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ITGA6 integrin, alpha 6
ITGB4 integrin, beta 4
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LEF1 lymphoid enhancer-binding factor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LPPR1 lipid phosphate phosphatase-related protein type 1
MEF2C myocyte enhancer factor 2C
NDNF neuron-derived neurotrophic factor
NEFH neurofilament, heavy polypeptide
PODXL podocalyxin-like
PTN pleiotrophin
RAB25 RAB25, member RAS oncogene family
REEP1 receptor accessory protein 1
RGS1 regulator of G-protein signaling 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SAT1 spermidine/spermine N1-acetyltransferase 1
SKAP2 src kinase associated phosphoprotein 2
TACSTD2 tumor-associated calcium signal transducer 2
TMEM255A transmembrane protein 255A
TMEM87A transmembrane protein 87A