BRD-K86856088_UNC0638_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K86856088_UNC0638_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
ALDOC aldolase C, fructose-bisphosphate
ANXA2 annexin A2
ARL4C ADP-ribosylation factor-like 4C
ATG3 autophagy related 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
C1ORF116 chromosome 1 open reading frame 116
CCND2 cyclin D2
CD52 CD52 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES1 carboxylesterase 1
CLDN1 claudin 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
EBP emopamil binding protein (sterol isomerase)
EPAS1 endothelial PAS domain protein 1
FBLN1 fibulin 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GHR growth hormone receptor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KLF4 Kruppel-like factor 4 (gut)
KYNU kynureninase
LCN2 lipocalin 2
LMO3 LIM domain only 3 (rhombotin-like 2)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MDFIC MyoD family inhibitor domain containing
MGP matrix Gla protein
PALLD palladin, cytoskeletal associated protein
PERP PERP, TP53 apoptosis effector
PROM1 prominin 1
PTCH1 patched 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RND3 Rho family GTPase 3
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A10 S100 calcium binding protein A10
SPINK1 serine peptidase inhibitor, Kazal type 1
SQSTM1 sequestosome 1
ST18 suppression of tumorigenicity 18, zinc finger
STC2 stanniocalcin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM97 transmembrane protein 97
TP53I3 tumor protein p53 inducible protein 3
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
TTR transthyretin
WLS wntless Wnt ligand secretion mediator
WNT5A wingless-type MMTV integration site family, member 5A
ZNF423 zinc finger protein 423
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
BAD BCL2-associated agonist of cell death
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CALML5 calmodulin-like 5
CRYAB crystallin, alpha B
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
HSPA2 heat shock 70kDa protein 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIAA0101 KIAA0101
KRT14 keratin 14, type I
MATN2 matrilin 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUSAP1 nucleolar and spindle associated protein 1
NVL nuclear VCP-like
PLAT plasminogen activator, tissue
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PTPRE protein tyrosine phosphatase, receptor type, E
PUF60 poly-U binding splicing factor 60KDa
STK17B serine/threonine kinase 17b
THY1 Thy-1 cell surface antigen
TPM4 tropomyosin 4
WT1 Wilms tumor 1
YBX3 Y box binding protein 3