BRD-K84924563_6-diazo-5-oxo-l-norleucine_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K84924563_6-diazo-5-oxo-l-norleucine_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
CALR calreticulin
CDH3 cadherin 3, type 1, P-cadherin (placental)
CNPY3 canopy FGF signaling regulator 3
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
CXCL8 chemokine (C-X-C motif) ligand 8
F11R F11 receptor
FAM129A family with sequence similarity 129, member A
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLRX glutaredoxin (thioltransferase)
HHEX hematopoietically expressed homeobox
IPO13 importin 13
JAG1 jagged 1
KRT15 keratin 15, type I
KRT18 keratin 18, type I
KRT6A keratin 6A, type II
LDOC1 leucine zipper, down-regulated in cancer 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MNDA myeloid cell nuclear differentiation antigen
MZB1 marginal zone B and B1 cell-specific protein
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
RNH1 ribonuclease/angiogenin inhibitor 1
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SFRP1 secreted frizzled-related protein 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STC1 stanniocalcin 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN7 tetraspanin 7
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A
YBX3 Y box binding protein 3

decreased expression

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C1QTNF3 C1q and tumor necrosis factor related protein 3
C6ORF62 chromosome 6 open reading frame 62
CDKN3 cyclin-dependent kinase inhibitor 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DCN decorin
EIF4B eukaryotic translation initiation factor 4B
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
HOXC6 homeobox C6
PRR7 proline rich 7 (synaptic)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
SATB1 SATB homeobox 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC35F2 solute carrier family 35, member F2
TM4SF1 transmembrane 4 L six family member 1
TMEM106B transmembrane protein 106B
TSPAN13 tetraspanin 13