BRD-K84924563_6-diazo-5-oxo-l-norleucine_SW620_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K84924563_6-diazo-5-oxo-l-norleucine_SW620_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTB actin, beta
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
APP amyloid beta (A4) precursor protein
CA2 carbonic anhydrase II
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
COLEC12 collectin sub-family member 12
DEPTOR DEP domain containing MTOR-interacting protein
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
DUOX2 dual oxidase 2
EDN1 endothelin 1
EIF1 eukaryotic translation initiation factor 1
GJA1 gap junction protein, alpha 1, 43kDa
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GULP1 GULP, engulfment adaptor PTB domain containing 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MAN1A1 mannosidase, alpha, class 1A, member 1
MEST mesoderm specific transcript
MN1 meningioma (disrupted in balanced translocation) 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORC1 origin recognition complex, subunit 1
PDZK1IP1 PDZK1 interacting protein 1
PLAC8 placenta-specific 8
PLS3 plastin 3
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RALB v-ral simian leukemia viral oncogene homolog B
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A7 S100 calcium binding protein A7
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
TMC5 transmembrane channel-like 5
TSPAN8 tetraspanin 8
UBE2A ubiquitin-conjugating enzyme E2A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
APOLD1 apolipoprotein L domain containing 1
ARL4C ADP-ribosylation factor-like 4C
BST2 bone marrow stromal cell antigen 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK6 cyclin-dependent kinase 6
CFD complement factor D (adipsin)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DIXDC1 DIX domain containing 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM46A family with sequence similarity 46, member A
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
FXYD1 FXYD domain containing ion transport regulator 1
GPM6B glycoprotein M6B
IGFBP3 insulin-like growth factor binding protein 3
IL7R interleukin 7 receptor
ITGA7 integrin, alpha 7
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF14 kinesin family member 14
METTL7A methyltransferase like 7A
MT1X metallothionein 1X
PLTP phospholipid transfer protein
RBL2 retinoblastoma-like 2
RHOBTB3 Rho-related BTB domain containing 3
S100A2 S100 calcium binding protein A2
SLC38A1 solute carrier family 38, member 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNNT1 troponin T type 1 (skeletal, slow)
TRIB2 tribbles pseudokinase 2
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF91 zinc finger protein 91