BRD-K84924563_6-diazo-5-oxo-l-norleucine_MCF7_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

100 genes differentially expressed following the BRD-K84924563_6-diazo-5-oxo-l-norleucine_MCF7_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ANGPT2 angiopoietin 2
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BTG2 BTG family, member 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CPE carboxypeptidase E
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL9 chemokine (C-X-C motif) ligand 9
DST dystonin
EXT1 exostosin glycosyltransferase 1
FAM129A family with sequence similarity 129, member A
FAM69A family with sequence similarity 69, member A
FILIP1L filamin A interacting protein 1-like
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KDR kinase insert domain receptor
KRT15 keratin 15, type I
KRT6A keratin 6A, type II
LPAR6 lysophosphatidic acid receptor 6
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MEST mesoderm specific transcript
NSDHL NAD(P) dependent steroid dehydrogenase-like
NVL nuclear VCP-like
PCDH7 protocadherin 7
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PMM2 phosphomannomutase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RND3 Rho family GTPase 3
RTN1 reticulon 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SHB Src homology 2 domain containing adaptor protein B
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPRED2 sprouty-related, EVH1 domain containing 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TES testin LIM domain protein
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
AGR2 anterior gradient 2
AK1 adenylate kinase 1
ANGPT1 angiopoietin 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARG1 arginase 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BAALC brain and acute leukemia, cytoplasmic
C6ORF62 chromosome 6 open reading frame 62
CCND1 cyclin D1
CHPT1 choline phosphotransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
ECI2 enoyl-CoA delta isomerase 2
EGR3 early growth response 3
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FOLR1 folate receptor 1 (adult)
FZD7 frizzled class receptor 7
GSTM3 glutathione S-transferase mu 3 (brain)
HOXC6 homeobox C6
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF6 Kruppel-like factor 6
LPL lipoprotein lipase
LTF lactotransferrin
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MGP matrix Gla protein
NPR3 natriuretic peptide receptor 3
PEBP1 phosphatidylethanolamine binding protein 1
PGC progastricsin (pepsinogen C)
PLEC plectin
PLK1 polo-like kinase 1
PRSS3 protease, serine, 3
PTX3 pentraxin 3, long
RGS4 regulator of G-protein signaling 4
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A12 S100 calcium binding protein A12
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SOX9 SRY (sex determining region Y)-box 9
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TSPAN8 tetraspanin 8