BRD-K84924563_6-diazo-5-oxo-l-norleucine_HCC515_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

15 genes differentially expressed following the BRD-K84924563_6-diazo-5-oxo-l-norleucine_HCC515_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
DLK1 delta-like 1 homolog (Drosophila)
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGHM immunoglobulin heavy constant mu
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND1 cyclin D1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL5 chemokine (C-X-C motif) ligand 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
S100B S100 calcium binding protein B