BRD-K84924563_6-diazo-5-oxo-l-norleucine_A673_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-K84924563_6-diazo-5-oxo-l-norleucine_A673_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADAMDEC1 ADAM-like, decysin 1
AHR aryl hydrocarbon receptor
C3 complement component 3
CCL19 chemokine (C-C motif) ligand 19
CD69 CD69 molecule
CFB complement factor B
CLDN4 claudin 4
CLIC4 chloride intracellular channel 4
CRYZ crystallin, zeta (quinone reductase)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL13 chemokine (C-X-C motif) ligand 13
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DSP desmoplakin
EHF ets homologous factor
FXYD3 FXYD domain containing ion transport regulator 3
FZD6 frizzled class receptor 6
GDF15 growth differentiation factor 15
GLS glutaminase
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFI27 interferon, alpha-inducible protein 27
IFIH1 interferon induced with helicase C domain 1
JCHAIN joining chain of multimeric IgA and IgM
KLK5 kallikrein-related peptidase 5
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KYNU kynureninase
LUM lumican
MAGEA3 melanoma antigen family A3
MAP7 microtubule-associated protein 7
MB myoglobin
MBP myelin basic protein
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP7 matrix metallopeptidase 7
MPZL2 myelin protein zero-like 2
MTERF3 mitochondrial transcription termination factor 3
MYO6 myosin VI
OPN3 opsin 3
PAM peptidylglycine alpha-amidating monooxygenase
PERP PERP, TP53 apoptosis effector
PHACTR2 phosphatase and actin regulator 2
PLAGL1 pleiomorphic adenoma gene-like 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PRAME preferentially expressed antigen in melanoma
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS1 regulator of G-protein signaling 1
SCAMP1 secretory carrier membrane protein 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
STK26 serine/threonine protein kinase 26
TACSTD2 tumor-associated calcium signal transducer 2
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM123 transmembrane protein 123
TUSC3 tumor suppressor candidate 3
UBE2A ubiquitin-conjugating enzyme E2A
VWA5A von Willebrand factor A domain containing 5A
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AZU1 azurocidin 1
B3GNT1
CLC Charcot-Leyden crystal galectin
CXCL12 chemokine (C-X-C motif) ligand 12
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DPYSL3 dihydropyrimidinase-like 3
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ENO1 enolase 1, (alpha)
FGFR1 fibroblast growth factor receptor 1
G0S2 G0/G1 switch 2
GPI glucose-6-phosphate isomerase
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HBB hemoglobin, beta
KIAA0100 KIAA0100
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
ORC1 origin recognition complex, subunit 1
PEBP1 phosphatidylethanolamine binding protein 1
PRDX2 peroxiredoxin 2
PRTN3 proteinase 3
PSAP prosaposin
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TREM1 triggering receptor expressed on myeloid cells 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAN versican
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF586 zinc finger protein 586