BRD-K84881516_Thiophene-2-carboxylic acid benzothiazol-2-ylamide MLS-0446110.0001_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K84881516_Thiophene-2-carboxylic acid benzothiazol-2-ylamide MLS-0446110.0001_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANXA1 annexin A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC4 chloride intracellular channel 4
DDIT4 DNA-damage-inducible transcript 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ERBB2 erb-b2 receptor tyrosine kinase 2
GCH1 GTP cyclohydrolase 1
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
INSIG1 insulin induced gene 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MET MET proto-oncogene, receptor tyrosine kinase
MICALL1 MICAL-like 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
NRIP1 nuclear receptor interacting protein 1
PDGFC platelet derived growth factor C
RNF6 ring finger protein (C3H2C3 type) 6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGK1 serum/glucocorticoid regulated kinase 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STXBP1 syntaxin binding protein 1
TAGLN transgelin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TXNRD1 thioredoxin reductase 1
UBE3C ubiquitin protein ligase E3C

decreased expression

Symbol Name
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
IFITM1 interferon induced transmembrane protein 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
ZW10 zw10 kinetochore protein