BRD-K84881516_Thiophene-2-carboxylic acid benzothiazol-2-ylamide MLS-0446110.0001_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K84881516_Thiophene-2-carboxylic acid benzothiazol-2-ylamide MLS-0446110.0001_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AK1 adenylate kinase 1
CA12 carbonic anhydrase XII
CHI3L2 chitinase 3-like 2
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA1A heat shock 70kDa protein 1A
IGFBP4 insulin-like growth factor binding protein 4
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLHL21 kelch-like family member 21
PRKCA protein kinase C, alpha
PRPF4 pre-mRNA processing factor 4
RHOBTB3 Rho-related BTB domain containing 3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SPATS2L spermatogenesis associated, serine-rich 2-like
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AHSG alpha-2-HS-glycoprotein
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
BEX1 brain expressed, X-linked 1
CLC Charcot-Leyden crystal galectin
CXCL11 chemokine (C-X-C motif) ligand 11
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP1 fatty acid binding protein 1, liver
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
GPNMB glycoprotein (transmembrane) nmb
KRAS Kirsten rat sarcoma viral oncogene homolog
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
S100A8 S100 calcium binding protein A8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SOX11 SRY (sex determining region Y)-box 11
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1