BRD-K84709232_Caffeic acid phenethyl ester_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K84709232_Caffeic acid phenethyl ester_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C1QB complement component 1, q subcomponent, B chain
C3 complement component 3
CCND2 cyclin D2
CD163 CD163 molecule
CD24 CD24 molecule
CKB creatine kinase, brain
CLEC2B C-type lectin domain family 2, member B
COL15A1 collagen, type XV, alpha 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CRISP3 cysteine-rich secretory protein 3
CYBB cytochrome b-245, beta polypeptide
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP6 dual specificity phosphatase 6
FTH1 ferritin, heavy polypeptide 1
GCLC glutamate-cysteine ligase, catalytic subunit
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1C histone cluster 1, H1c
HK2 hexokinase 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IRS2 insulin receptor substrate 2
JCHAIN joining chain of multimeric IgA and IgM
KCNK3 potassium channel, two pore domain subfamily K, member 3
LGALS8 lectin, galactoside-binding, soluble, 8
LIMCH1 LIM and calponin homology domains 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NUPR1 nuclear protein, transcriptional regulator, 1
PDIA3 protein disulfide isomerase family A, member 3
PLAGL1 pleiomorphic adenoma gene-like 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGCC regulator of cell cycle
RNASE4 ribonuclease, RNase A family, 4
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM2 tripartite motif containing 2
VEGFA vascular endothelial growth factor A
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ALCAM activated leukocyte cell adhesion molecule
AURKA aurora kinase A
CCNF cyclin F
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
CHL1 cell adhesion molecule L1-like
CKS2 CDC28 protein kinase regulatory subunit 2
DLC1 DLC1 Rho GTPase activating protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMTF1 cyclin D binding myb-like transcription factor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
HLTF helicase-like transcription factor
HMMR hyaluronan-mediated motility receptor (RHAMM)
KNG1 kininogen 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMP5 lysosomal-associated membrane protein family, member 5
MBNL2 muscleblind-like splicing regulator 2
MRPS33 mitochondrial ribosomal protein S33
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBK PDZ binding kinase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK1 polo-like kinase 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RPS11 ribosomal protein S11
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYT1 synaptotagmin I
TSPAN8 tetraspanin 8
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
ZBTB20 zinc finger and BTB domain containing 20