BRD-K84709232_Caffeic acid phenethyl ester_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

231 genes differentially expressed following the BRD-K84709232_Caffeic acid phenethyl ester_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACKR3 atypical chemokine receptor 3
ACP2 acid phosphatase 2, lysosomal
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BSG basigin (Ok blood group)
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF132 chromosome 14 open reading frame 132
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CANX calnexin
CD14 CD14 molecule
CD163 CD163 molecule
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFD complement factor D (adipsin)
CLCA2 chloride channel accessory 2
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COL2A1 collagen, type II, alpha 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELANE elastase, neutrophil expressed
ELMO1 engulfment and cell motility 1
ENO2 enolase 2 (gamma, neuronal)
FAF2 Fas associated factor family member 2
FAM46A family with sequence similarity 46, member A
FAM46C family with sequence similarity 46, member C
FCGBP Fc fragment of IgG binding protein
FKBP11 FK506 binding protein 11, 19 kDa
FOXO4 forkhead box O4
GABARAPL1 GABA(A) receptor-associated protein like 1
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GNLY granulysin
GOLT1B golgi transport 1B
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRN granulin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HIRA histone cell cycle regulator
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IL13RA2 interleukin 13 receptor, alpha 2
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
LAMP2 lysosomal-associated membrane protein 2
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC399491
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP7 microtubule-associated protein 7
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MMP9 matrix metallopeptidase 9
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
N4BP2L1 NEDD4 binding protein 2-like 1
NDRG2 NDRG family member 2
NUCB2 nucleobindin 2
PCDH9 protocadherin 9
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4DIP phosphodiesterase 4D interacting protein
PDIA3 protein disulfide isomerase family A, member 3
PERP PERP, TP53 apoptosis effector
PHGDH phosphoglycerate dehydrogenase
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLIN2 perilipin 2
PMM2 phosphomannomutase 2
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROM1 prominin 1
PRTN3 proteinase 3
PRUNE2 prune homolog 2 (Drosophila)
PSAP prosaposin
PTPRO protein tyrosine phosphatase, receptor type, O
RABAC1 Rab acceptor 1 (prenylated)
RPRD2 regulation of nuclear pre-mRNA domain containing 2
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC62 SEC62 homolog (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
SPRED2 sprouty-related, EVH1 domain containing 2
SQSTM1 sequestosome 1
SSR4 signal sequence receptor, delta
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TRIB3 tribbles pseudokinase 3
TSPAN13 tetraspanin 13
USP3 ubiquitin specific peptidase 3
VEGFA vascular endothelial growth factor A
WFDC1 WAP four-disulfide core domain 1
XBP1 X-box binding protein 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF292 zinc finger protein 292

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTA2 actin, alpha 2, smooth muscle, aorta
ALB albumin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
C7 complement component 7
CALB1 calbindin 1, 28kDa
CALD1 caldesmon 1
CARD10 caspase recruitment domain family, member 10
CCL2 chemokine (C-C motif) ligand 2
CCNE2 cyclin E2
CD59 CD59 molecule, complement regulatory protein
CFLAR CASP8 and FADD-like apoptosis regulator
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COL1A2 collagen, type I, alpha 2
COL6A3 collagen, type VI, alpha 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSV cathepsin V
DAPK1 death-associated protein kinase 1
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DEFB1 defensin, beta 1
DHCR24 24-dehydrocholesterol reductase
EFNB2 ephrin-B2
EGF epidermal growth factor
EHD1 EH-domain containing 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBN1 fibrillin 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FXYD2 FXYD domain containing ion transport regulator 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX1 glutathione peroxidase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ICAM1 intercellular adhesion molecule 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCTD12 potassium channel tetramerization domain containing 12
KLF6 Kruppel-like factor 6
KNG1 kininogen 1
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LDLR low density lipoprotein receptor
LMCD1 LIM and cysteine-rich domains 1
LMNA lamin A/C
LRRC17 leucine rich repeat containing 17
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAGEA12 melanoma antigen family A12
MGP matrix Gla protein
MOK MOK protein kinase
MSMO1 methylsterol monooxygenase 1
MUC16 mucin 16, cell surface associated
MVP major vault protein
MYLK myosin light chain kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPR3 natriuretic peptide receptor 3
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDGFC platelet derived growth factor C
PDLIM1 PDZ and LIM domain 1
PDZK1 PDZ domain containing 1
PEG10 paternally expressed 10
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
POSTN periostin, osteoblast specific factor
PRSS23 protease, serine, 23
PSPH phosphoserine phosphatase
QKI QKI, KH domain containing, RNA binding
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RBM47 RNA binding motif protein 47
RBP1 retinol binding protein 1, cellular
RCAN1 regulator of calcineurin 1
RGS4 regulator of G-protein signaling 4
RPL37A ribosomal protein L37a
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSU1 Ras suppressor protein 1
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
SDC4 syndecan 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SQLE squalene epoxidase
STK17A serine/threonine kinase 17a
TACSTD2 tumor-associated calcium signal transducer 2
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TJP2 tight junction protein 2
TMPRSS3 transmembrane protease, serine 3
TNC tenascin C
TNS1 tensin 1
TRAPPC4 trafficking protein particle complex 4
TSPAN8 tetraspanin 8
VCL vinculin
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF185 zinc finger protein 185 (LIM domain)