BRD-K83972459_JWE-035_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K83972459_JWE-035_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA4 annexin A4
CKB creatine kinase, brain
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CXCL13 chemokine (C-X-C motif) ligand 13
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETV5 ets variant 5
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
GMPR guanosine monophosphate reductase
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HPCAL1 hippocalcin-like 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFI6 interferon, alpha-inducible protein 6
ITGA6 integrin, alpha 6
KDM5D lysine (K)-specific demethylase 5D
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAGEA3 melanoma antigen family A3
MT1M metallothionein 1M
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLIN2 perilipin 2
QPCT glutaminyl-peptide cyclotransferase
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFTPB surfactant protein B
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SRGN serglycin
STAT1 signal transducer and activator of transcription 1, 91kDa
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TPP1 tripeptidyl peptidase I
TRIM2 tripartite motif containing 2
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CBR3 carbonyl reductase 3
CD14 CD14 molecule
COL5A2 collagen, type V, alpha 2
CORO1A coronin, actin binding protein, 1A
CX3CR1 chemokine (C-X3-C motif) receptor 1
DPYD dihydropyrimidine dehydrogenase
ESR1 estrogen receptor 1
EXOSC4 exosome component 4
F13A1 coagulation factor XIII, A1 polypeptide
FCGBP Fc fragment of IgG binding protein
FGFBP1 fibroblast growth factor binding protein 1
HOMER3 homer scaffolding protein 3
HTRA1 HtrA serine peptidase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IPO13 importin 13
KLK5 kallikrein-related peptidase 5
KRT5 keratin 5, type II
LEF1 lymphoid enhancer-binding factor 1
MFAP2 microfibrillar-associated protein 2
MRPS16 mitochondrial ribosomal protein S16
NMI N-myc (and STAT) interactor
NRN1 neuritin 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PEX11A peroxisomal biogenesis factor 11 alpha
PIP prolactin-induced protein
POSTN periostin, osteoblast specific factor
RIN2 Ras and Rab interactor 2
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SAMD4A sterile alpha motif domain containing 4A
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SNX7 sorting nexin 7
TF transferrin
THBS4 thrombospondin 4
TPBG trophoblast glycoprotein
VCAN versican
XIST X inactive specific transcript (non-protein coding)
ZFP36L1 ZFP36 ring finger protein-like 1