BRD-K83972459_JWE-035_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K83972459_JWE-035_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
AGTR1 angiotensin II receptor, type 1
APOD apolipoprotein D
ASMTL acetylserotonin O-methyltransferase-like
ASS1 argininosuccinate synthase 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BASP1 brain abundant, membrane attached signal protein 1
CCL19 chemokine (C-C motif) ligand 19
CHRDL1 chordin-like 1
CTGF connective tissue growth factor
DUSP3 dual specificity phosphatase 3
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GPX1 glutathione peroxidase 1
GREB1 growth regulation by estrogen in breast cancer 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BG histone cluster 1, H2bg
HIST1H3H histone cluster 1, H3h
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
MT1E metallothionein 1E
MT1H metallothionein 1H
PCDH9 protocadherin 9
PDZK1 PDZ domain containing 1
PLA1A phospholipase A1 member A
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SORBS1 sorbin and SH3 domain containing 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TXNIP thioredoxin interacting protein
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CA12 carbonic anhydrase XII
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHN1 chimerin 1
CSTA cystatin A (stefin A)
DESI2 desumoylating isopeptidase 2
GLUL glutamate-ammonia ligase
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KRT19 keratin 19, type I
LAPTM4B lysosomal protein transmembrane 4 beta
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
NDP Norrie disease (pseudoglioma)
PDGFC platelet derived growth factor C
PDLIM1 PDZ and LIM domain 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLAUR plasminogen activator, urokinase receptor
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
RAB25 RAB25, member RAS oncogene family
RFC2 replication factor C (activator 1) 2, 40kDa
RNF144A ring finger protein 144A
RPS5 ribosomal protein S5
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SOX11 SRY (sex determining region Y)-box 11
SPTSSA serine palmitoyltransferase, small subunit A
TES testin LIM domain protein
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPD52L1 tumor protein D52-like 1
TRIM2 tripartite motif containing 2
TTC3 tetratricopeptide repeat domain 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon