BRD-K83963101_MLN-8054_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K83963101_MLN-8054_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AHNAK AHNAK nucleoprotein
APOLD1 apolipoprotein L domain containing 1
C1QB complement component 1, q subcomponent, B chain
C8ORF4 chromosome 8 open reading frame 4
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CORO1A coronin, actin binding protein, 1A
CPA3 carboxypeptidase A3 (mast cell)
CXADR coxsackie virus and adenovirus receptor
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DCLK1 doublecortin-like kinase 1
DLC1 DLC1 Rho GTPase activating protein
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FABP4 fatty acid binding protein 4, adipocyte
FAM107A family with sequence similarity 107, member A
FBN2 fibrillin 2
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GRB10 growth factor receptor-bound protein 10
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AE histone cluster 1, H2ae
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
LMO3 LIM domain only 3 (rhombotin-like 2)
LMO4 LIM domain only 4
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFAP5 microfibrillar associated protein 5
MRPS16 mitochondrial ribosomal protein S16
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO1B myosin IB
MYO6 myosin VI
ODC1 ornithine decarboxylase 1
OSBPL1A oxysterol binding protein-like 1A
PIP prolactin-induced protein
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PXDN peroxidasin
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100P S100 calcium binding protein P
SLC38A1 solute carrier family 38, member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF1 trefoil factor 1
TMEM100 transmembrane protein 100
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPD52 tumor protein D52
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C14ORF132 chromosome 14 open reading frame 132
CD200 CD200 molecule
FAM129A family with sequence similarity 129, member A
GPATCH8 G patch domain containing 8
GSTO1 glutathione S-transferase omega 1
HBB hemoglobin, beta
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
MT1E metallothionein 1E
MX1 MX dynamin-like GTPase 1
PTN pleiotrophin
RAI14 retinoic acid induced 14
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)