BRD-K83963101_MLN-8054_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

18 genes differentially expressed following the BRD-K83963101_MLN-8054_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL5 chemokine (C-C motif) ligand 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDB2 damage-specific DNA binding protein 2, 48kDa
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
GADD45A growth arrest and DNA-damage-inducible, alpha
KRT14 keratin 14, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
SESN1 sestrin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TUSC3 tumor suppressor candidate 3

decreased expression

Symbol Name
CDC25A cell division cycle 25A
CYBA cytochrome b-245, alpha polypeptide
FBLN5 fibulin 5
GAL galanin/GMAP prepropeptide
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HSPA2 heat shock 70kDa protein 2