BRD-K83778500_AT-CSC-18 BRD-K01121114_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K83778500_AT-CSC-18 BRD-K01121114_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CA12 carbonic anhydrase XII
CD69 CD69 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLU clusterin
DUSP22 dual specificity phosphatase 22
HIST3H2A histone cluster 3, H2a
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PROM1 prominin 1
RAB25 RAB25, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SESN1 sestrin 1
SNX11 sorting nexin 11
TRIP6 thyroid hormone receptor interactor 6

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRG6 adhesion G protein-coupled receptor G6
C7 complement component 7
CPE carboxypeptidase E
CXCL9 chemokine (C-X-C motif) ligand 9
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
FABP7 fatty acid binding protein 7, brain
HK2 hexokinase 2
MARCKSL1 MARCKS-like 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
SCGB1D2 secretoglobin, family 1D, member 2
SERINC5 serine incorporator 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase