BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_VCAP_6.0_h_6.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_VCAP_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BASP1 brain abundant, membrane attached signal protein 1
CPA3 carboxypeptidase A3 (mast cell)
CPD carboxypeptidase D
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DPP4 dipeptidyl-peptidase 4
DUSP1 dual specificity phosphatase 1
HMOX1 heme oxygenase 1
ITM2A integral membrane protein 2A
MAP7 microtubule-associated protein 7
MDFIC MyoD family inhibitor domain containing
MFAP5 microfibrillar associated protein 5
MUC4 mucin 4, cell surface associated
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NEFH neurofilament, heavy polypeptide
NID2 nidogen 2 (osteonidogen)
NQO1 NAD(P)H dehydrogenase, quinone 1
PBX1 pre-B-cell leukemia homeobox 1
PERP PERP, TP53 apoptosis effector
S100P S100 calcium binding protein P
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SRGN serglycin
TMEM47 transmembrane protein 47
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
C1R complement component 1, r subcomponent
COPS7A COP9 signalosome subunit 7A
CP ceruloplasmin (ferroxidase)
EIF5 eukaryotic translation initiation factor 5
EMP1 epithelial membrane protein 1
ENO2 enolase 2 (gamma, neuronal)
HPCAL1 hippocalcin-like 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MAGEA3 melanoma antigen family A3
MAOB monoamine oxidase B
MAT2A methionine adenosyltransferase II, alpha
MSMO1 methylsterol monooxygenase 1
MT1E metallothionein 1E
NREP neuronal regeneration related protein
PNMAL1 paraneoplastic Ma antigen family-like 1
PRKCDBP protein kinase C, delta binding protein
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
STK39 serine threonine kinase 39
TRIB2 tribbles pseudokinase 2
TUBB2B tubulin, beta 2B class IIb
VCAM1 vascular cell adhesion molecule 1
ZMIZ1 zinc finger, MIZ-type containing 1