BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_PC3_6.0_h_6.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_PC3_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CD163 CD163 molecule
ESR1 estrogen receptor 1
FAM46A family with sequence similarity 46, member A
FGFR1 fibroblast growth factor receptor 1
FOLR1 folate receptor 1 (adult)
GNAS GNAS complex locus
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SELENBP1 selenium binding protein 1
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DFNA5 deafness, autosomal dominant 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
G0S2 G0/G1 switch 2
IDO1 indoleamine 2,3-dioxygenase 1
IL1B interleukin 1, beta
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT14 keratin 14, type I
RBP4 retinol binding protein 4, plasma
RPA3 replication protein A3, 14kDa
S100A2 S100 calcium binding protein A2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPRED2 sprouty-related, EVH1 domain containing 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase