BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_6.0_h_6.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CLDN10 claudin 10
GPM6B glycoprotein M6B
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
SELENBP1 selenium binding protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TBXA2R thromboxane A2 receptor
TRIM2 tripartite motif containing 2
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
BIK BCL2-interacting killer (apoptosis-inducing)
CD24 CD24 molecule
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FABP4 fatty acid binding protein 4, adipocyte
KLF10 Kruppel-like factor 10
POU2AF1 POU class 2 associating factor 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIK1 salt-inducible kinase 1
SQLE squalene epoxidase
STK39 serine threonine kinase 39
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
UGCG UDP-glucose ceramide glucosyltransferase
ZMIZ1 zinc finger, MIZ-type containing 1