BRD-K83194053_4-(2-(6-chloroquinazolin-4-ylamino)ethyl)phenol CU-00000000029-2_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K83194053_4-(2-(6-chloroquinazolin-4-ylamino)ethyl)phenol CU-00000000029-2_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
BRCA1 breast cancer 1, early onset
CALCA calcitonin-related polypeptide alpha
CCND1 cyclin D1
CHEK2 checkpoint kinase 2
CXCL14 chemokine (C-X-C motif) ligand 14
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FABP7 fatty acid binding protein 7, brain
HES1 hes family bHLH transcription factor 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IGFBP3 insulin-like growth factor binding protein 3
IGLL1 immunoglobulin lambda-like polypeptide 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOLC1 nucleolar and coiled-body phosphoprotein 1
OLFM1 olfactomedin 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RRAGD Ras-related GTP binding D
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TBC1D16 TBC1 domain family, member 16
TYRP1 tyrosinase-related protein 1

decreased expression

Symbol Name
CA2 carbonic anhydrase II
COL4A5 collagen, type IV, alpha 5
CST3 cystatin C
KRT8 keratin 8, type II
MEIS2 Meis homeobox 2
MIR22HG MIR22 host gene
NRIP1 nuclear receptor interacting protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RAI14 retinoic acid induced 14
RNH1 ribonuclease/angiogenin inhibitor 1
S100A10 S100 calcium binding protein A10
SCAND1 SCAN domain containing 1
TFPI2 tissue factor pathway inhibitor 2