BRD-K82928847_rocilinostat_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

82 genes differentially expressed following the BRD-K82928847_rocilinostat_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AMDHD2 amidohydrolase domain containing 2
APOD apolipoprotein D
CRIP2 cysteine-rich protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL5 chemokine (C-X-C motif) ligand 5
DDIT4 DNA-damage-inducible transcript 4
DHRS7 dehydrogenase/reductase (SDR family) member 7
FADS1 fatty acid desaturase 1
FAM65B family with sequence similarity 65, member B
FGF13 fibroblast growth factor 13
FN1 fibronectin 1
FOXO4 forkhead box O4
GDF15 growth differentiation factor 15
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ISG15 ISG15 ubiquitin-like modifier
LOC100505650 uncharacterized LOC100505650
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1A1 mannosidase, alpha, class 1A, member 1
MBNL2 muscleblind-like splicing regulator 2
MSX1 msh homeobox 1
MX2 MX dynamin-like GTPase 2
NDRG1 N-myc downstream regulated 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NRN1 neuritin 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PMP22 peripheral myelin protein 22
RIPK4 receptor-interacting serine-threonine kinase 4
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RTN2 reticulon 2
STC1 stanniocalcin 1
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM9SF3 transmembrane 9 superfamily member 3
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VDAC1 voltage-dependent anion channel 1
ZMYM2 zinc finger, MYM-type 2
ZNF274 zinc finger protein 274
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
ASS1 argininosuccinate synthase 1
CA12 carbonic anhydrase XII
CCNB1 cyclin B1
COL15A1 collagen, type XV, alpha 1
COL3A1 collagen, type III, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CTSS cathepsin S
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
FBLN1 fibulin 1
FERMT1 fermitin family member 1
G0S2 G0/G1 switch 2
GLUL glutamate-ammonia ligase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
HOXA5 homeobox A5
IGFBP5 insulin-like growth factor binding protein 5
KRT13 keratin 13, type I
LIMCH1 LIM and calponin homology domains 1
LMO2 LIM domain only 2 (rhombotin-like 1)
MECOM MDS1 and EVI1 complex locus
MMP12 matrix metallopeptidase 12
NEK2 NIMA-related kinase 2
NFE2L2 nuclear factor, erythroid 2-like 2
NUPR1 nuclear protein, transcriptional regulator, 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
POSTN periostin, osteoblast specific factor
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCAN2 regulator of calcineurin 2
S100A7 S100 calcium binding protein A7
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SPARCL1 SPARC-like 1 (hevin)
TCERG1 transcription elongation regulator 1
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B