BRD-K82928847_rocilinostat_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

84 genes differentially expressed following the BRD-K82928847_rocilinostat_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
ARL3 ADP-ribosylation factor-like 3
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMCX2 armadillo repeat containing, X-linked 2
CCND2 cyclin D2
CDC42 cell division cycle 42
CORO1C coronin, actin binding protein, 1C
DAD1 defender against cell death 1
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP6 dual specificity phosphatase 6
ESR1 estrogen receptor 1
EXOSC4 exosome component 4
FXYD6 FXYD domain containing ion transport regulator 6
GLOD4 glyoxalase domain containing 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KRT7 keratin 7, type II
LOC100505650 uncharacterized LOC100505650
LRP10 low density lipoprotein receptor-related protein 10
MMP7 matrix metallopeptidase 7
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
PALLD palladin, cytoskeletal associated protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIH1D1 PIH1 domain containing 1
PTN pleiotrophin
RBP1 retinol binding protein 1, cellular
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
S100A6 S100 calcium binding protein A6
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERINC5 serine incorporator 5
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SOX11 SRY (sex determining region Y)-box 11
SPON1 spondin 1, extracellular matrix protein
TACSTD2 tumor-associated calcium signal transducer 2
TFF1 trefoil factor 1
TGM2 transglutaminase 2
TNC tenascin C
TUBA1A tubulin, alpha 1a
WBP1L WW domain binding protein 1-like
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ATMIN ATM interactor
C1ORF115 chromosome 1 open reading frame 115
C2CD5 C2 calcium-dependent domain containing 5
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CSTA cystatin A (stefin A)
CTBP1 C-terminal binding protein 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
FAM129A family with sequence similarity 129, member A
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GPI glucose-6-phosphate isomerase
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
IGKV4-1 immunoglobulin kappa variable 4-1
MEOX2 mesenchyme homeobox 2
MTCL1 microtubule crosslinking factor 1
NAMPT nicotinamide phosphoribosyltransferase
NREP neuronal regeneration related protein
PCSK6 proprotein convertase subtilisin/kexin type 6
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIC peptidylprolyl isomerase C (cyclophilin C)
PROS1 protein S (alpha)
PTK2 protein tyrosine kinase 2
RTN1 reticulon 1
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
VDAC1 voltage-dependent anion channel 1
VWF von Willebrand factor