BRD-K82928847_rocilinostat_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K82928847_rocilinostat_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP9A ATPase, class II, type 9A
BTG3 BTG family, member 3
CALML5 calmodulin-like 5
CAST calpastatin
CD59 CD59 molecule, complement regulatory protein
CHPT1 choline phosphotransferase 1
CRISP3 cysteine-rich secretory protein 3
CYFIP2 cytoplasmic FMR1 interacting protein 2
DHRS7 dehydrogenase/reductase (SDR family) member 7
ENO2 enolase 2 (gamma, neuronal)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FXYD2 FXYD domain containing ion transport regulator 2
GPER1 G protein-coupled estrogen receptor 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1F0 H1 histone family, member 0
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KRT7 keratin 7, type II
MBP myelin basic protein
MX1 MX dynamin-like GTPase 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
SCG5 secretogranin V
SDC2 syndecan 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCE sarcoglycan, epsilon
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC38A1 solute carrier family 38, member 1
SMAD1 SMAD family member 1
SOCS2 suppressor of cytokine signaling 2
STC1 stanniocalcin 1
STXBP2 syntaxin binding protein 2
THBS1 thrombospondin 1
TRD T cell receptor delta locus
TSC22D1 TSC22 domain family, member 1
WBP5 WW domain binding protein 5
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AGR2 anterior gradient 2
ASS1 argininosuccinate synthase 1
AUTS2 autism susceptibility candidate 2
BID BH3 interacting domain death agonist
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ELANE elastase, neutrophil expressed
EPAS1 endothelial PAS domain protein 1
FBP1 fructose-1,6-bisphosphatase 1
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KLK10 kallikrein-related peptidase 10
LRRN3 leucine rich repeat neuronal 3
LUM lumican
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MUC1 mucin 1, cell surface associated
PDE4B phosphodiesterase 4B, cAMP-specific
REG1A regenerating islet-derived 1 alpha
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAR steroidogenic acute regulatory protein
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFF1 trefoil factor 1
TSPAN8 tetraspanin 8