BRD-K82561139_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K82561139_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CAPN2 calpain 2, (m/II) large subunit
CSTA cystatin A (stefin A)
DFNA5 deafness, autosomal dominant 5
DUOX2 dual oxidase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HSPA1A heat shock 70kDa protein 1A
LDOC1 leucine zipper, down-regulated in cancer 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MECOM MDS1 and EVI1 complex locus
MYOF myoferlin
NEB nebulin
P3H2 prolyl 3-hydroxylase 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRL platelet-derived growth factor receptor-like
PNKP polynucleotide kinase 3'-phosphatase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCH protein kinase C, eta
SCGB2A2 secretoglobin, family 2A, member 2
SPON2 spondin 2, extracellular matrix protein
SUSD4 sushi domain containing 4
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPM2 tropomyosin 2 (beta)
TWIST1 twist family bHLH transcription factor 1
UGP2 UDP-glucose pyrophosphorylase 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOE apolipoprotein E
AQP3 aquaporin 3 (Gill blood group)
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
ATPIF1 ATPase inhibitory factor 1
CD24 CD24 molecule
CLIC4 chloride intracellular channel 4
COX5A cytochrome c oxidase subunit Va
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CYFIP2 cytoplasmic FMR1 interacting protein 2
GNAS GNAS complex locus
GPX3 glutathione peroxidase 3
GREM1 gremlin 1, DAN family BMP antagonist
HLA-B major histocompatibility complex, class I, B
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
MAP7 microtubule-associated protein 7
NEBL nebulette
PCSK1 proprotein convertase subtilisin/kexin type 1
PRDX2 peroxiredoxin 2
RNF167 ring finger protein 167
RPS26 ribosomal protein S26
S100P S100 calcium binding protein P
SEPT9 septin 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
STOM stomatin
STX1A syntaxin 1A (brain)
TNC tenascin C
ZDHHC11 zinc finger, DHHC-type containing 11