BRD-K82484347_GSK-J2_A375_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K82484347_GSK-J2_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
AK1 adenylate kinase 1
CD24 CD24 molecule
ERBB3 erb-b2 receptor tyrosine kinase 3
FOLR1 folate receptor 1 (adult)
GAS1 growth arrest-specific 1
HSPA2 heat shock 70kDa protein 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KLK6 kallikrein-related peptidase 6
KRT6B keratin 6B, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LXN latexin
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEBL nebulette
PERP PERP, TP53 apoptosis effector
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RNASE4 ribonuclease, RNase A family, 4
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPINK4 serine peptidase inhibitor, Kazal type 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR3 transforming growth factor, beta receptor III
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BPHL biphenyl hydrolase-like (serine hydrolase)
COL1A2 collagen, type I, alpha 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
FYB FYN binding protein
GLUL glutamate-ammonia ligase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LYPLA1 lysophospholipase I
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MPP1 membrane protein, palmitoylated 1, 55kDa
MSMB microseminoprotein, beta-
MT1F metallothionein 1F
PCP4 Purkinje cell protein 4
PECAM1 platelet/endothelial cell adhesion molecule 1
PTPRC protein tyrosine phosphatase, receptor type, C
RGCC regulator of cell cycle
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SHB Src homology 2 domain containing adaptor protein B
TGFA transforming growth factor, alpha
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRBC1 T cell receptor beta constant 1
ZMYM2 zinc finger, MYM-type 2