BRD-K81473043_-666_RMUGS_6.0_h_0.35_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K81473043_-666_RMUGS_6.0_h_0.35_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL5 acyl-CoA synthetase long-chain family member 5
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BAG3 BCL2-associated athanogene 3
BIN1 bridging integrator 1
BST2 bone marrow stromal cell antigen 2
CACYBP calcyclin binding protein
CDK6 cyclin-dependent kinase 6
CGRRF1 cell growth regulator with ring finger domain 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FAM46A family with sequence similarity 46, member A
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS1 lectin, galactoside-binding, soluble, 1
NOSIP nitric oxide synthase interacting protein
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PENK proenkephalin
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLK2 polo-like kinase 2
PTGES prostaglandin E synthase
QDPR quinoid dihydropteridine reductase
RBP1 retinol binding protein 1, cellular
RGS2 regulator of G-protein signaling 2
RNF114 ring finger protein 114
RPA3 replication protein A3, 14kDa
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SPATS2L spermatogenesis associated, serine-rich 2-like
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM97 transmembrane protein 97
TOMM34 translocase of outer mitochondrial membrane 34
TSC22D1 TSC22 domain family, member 1
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ARG2 arginase 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BGN biglycan
BLNK B-cell linker
CALML3 calmodulin-like 3
CD200 CD200 molecule
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CD9 CD9 molecule
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
CST1 cystatin SN
CXCL13 chemokine (C-X-C motif) ligand 13
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPYSL3 dihydropyrimidinase-like 3
EZR ezrin
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
GJA1 gap junction protein, alpha 1, 43kDa
HHEX hematopoietically expressed homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGHM immunoglobulin heavy constant mu
INA internexin neuronal intermediate filament protein, alpha
JAG1 jagged 1
KLK10 kallikrein-related peptidase 10
LCK LCK proto-oncogene, Src family tyrosine kinase
MEF2C myocyte enhancer factor 2C
MSMB microseminoprotein, beta-
MYH10 myosin, heavy chain 10, non-muscle
MYO1D myosin ID
NARFL nuclear prelamin A recognition factor-like
NINL ninein-like
NPIPB3 nuclear pore complex interacting protein family, member B3
PDLIM3 PDZ and LIM domain 3
PDZK1IP1 PDZK1 interacting protein 1
PPAP2B phosphatidic acid phosphatase type 2B
RGCC regulator of cell cycle
RHCG Rh family, C glycoprotein
RRAGD Ras-related GTP binding D
RTN2 reticulon 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TCF4 transcription factor 4
TNS1 tensin 1
TPD52 tumor protein D52
VCAN versican
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)