BRD-K81441552_8015-3528_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K81441552_8015-3528_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BAG3 BCL2-associated athanogene 3
CD24 CD24 molecule
CD69 CD69 molecule
CXCL12 chemokine (C-X-C motif) ligand 12
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
FHL1 four and a half LIM domains 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KLF9 Kruppel-like factor 9
MBP myelin basic protein
ORM1 orosomucoid 1
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SLC38A1 solute carrier family 38, member 1
TMEM45A transmembrane protein 45A

decreased expression

Symbol Name
BPHL biphenyl hydrolase-like (serine hydrolase)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL15A1 collagen, type XV, alpha 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
KRT7 keratin 7, type II
KRT81 keratin 81, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MSMO1 methylsterol monooxygenase 1
PDLIM5 PDZ and LIM domain 5
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SQLE squalene epoxidase
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZNF185 zinc finger protein 185 (LIM domain)