BRD-K81225797_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K81225797_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ASRGL1 asparaginase like 1
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
CCDC109B coiled-coil domain containing 109B
CD52 CD52 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHMP4A charged multivesicular body protein 4A
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC11A C-type lectin domain family 11, member A
CLIC4 chloride intracellular channel 4
CPM carboxypeptidase M
CXCL5 chemokine (C-X-C motif) ligand 5
EMP3 epithelial membrane protein 3
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
INHBA inhibin, beta A
KRT6B keratin 6B, type II
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MT1M metallothionein 1M
S100A8 S100 calcium binding protein A8
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4A1 solute carrier organic anion transporter family, member 4A1
TM4SF1 transmembrane 4 L six family member 1
TPD52 tumor protein D52
TRIM2 tripartite motif containing 2
TSPYL5 TSPY-like 5
TXNRD1 thioredoxin reductase 1
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
CXCL14 chemokine (C-X-C motif) ligand 14
ERAP2 endoplasmic reticulum aminopeptidase 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLRT3 fibronectin leucine rich transmembrane protein 3
FSD1 fibronectin type III and SPRY domain containing 1
GNAS GNAS complex locus
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHM immunoglobulin heavy constant mu
ISG15 ISG15 ubiquitin-like modifier
LAPTM4B lysosomal protein transmembrane 4 beta
MOXD1 monooxygenase, DBH-like 1
NOV nephroblastoma overexpressed
NREP neuronal regeneration related protein
PDGFC platelet derived growth factor C
RGS1 regulator of G-protein signaling 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SRSF6 serine/arginine-rich splicing factor 6
STK39 serine threonine kinase 39
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
XIST X inactive specific transcript (non-protein coding)