BRD-K79239947_PF 573228_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K79239947_PF 573228_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
C3ORF14 chromosome 3 open reading frame 14
CHI3L2 chitinase 3-like 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYAB crystallin, alpha B
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FGFR2 fibroblast growth factor receptor 2
GDF15 growth differentiation factor 15
GPR137B G protein-coupled receptor 137B
GSTP1 glutathione S-transferase pi 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HSPB8 heat shock 22kDa protein 8
IGKV1-5 immunoglobulin kappa variable 1-5
KAZN kazrin, periplakin interacting protein
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KDM5D lysine (K)-specific demethylase 5D
KRT7 keratin 7, type II
LBH limb bud and heart development
MT1M metallothionein 1M
NME4 NME/NM23 nucleoside diphosphate kinase 4
PCDH9 protocadherin 9
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLCB4 phospholipase C, beta 4
PTEN phosphatase and tensin homolog
PTN pleiotrophin
QPCT glutaminyl-peptide cyclotransferase
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAGD Ras-related GTP binding D
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFN stratifin
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TPD52 tumor protein D52
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C2CD5 C2 calcium-dependent domain containing 5
CCND1 cyclin D1
CLEC2B C-type lectin domain family 2, member B
CX3CR1 chemokine (C-X3-C motif) receptor 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GAGE3 G antigen 3
ISG15 ISG15 ubiquitin-like modifier
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT15 keratin 15, type I
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NOSIP nitric oxide synthase interacting protein
NT5E 5'-nucleotidase, ecto (CD73)
ODC1 ornithine decarboxylase 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SCG5 secretogranin V
SLC43A3 solute carrier family 43, member 3
SNX7 sorting nexin 7
TIMP3 TIMP metallopeptidase inhibitor 3
VNN1 vanin 1
XIST X inactive specific transcript (non-protein coding)