BRD-K79235952_ethyl 3-(methylthio)-4-oxo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate MAY_1_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K79235952_ethyl 3-(methylthio)-4-oxo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate MAY_1_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CD163 CD163 molecule
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EMP1 epithelial membrane protein 1
FGF13 fibroblast growth factor 13
FRZB frizzled-related protein
GPM6B glycoprotein M6B
GSTA4 glutathione S-transferase alpha 4
HMOX1 heme oxygenase 1
MAGED1 melanoma antigen family D1
MAOA monoamine oxidase A
MRPS16 mitochondrial ribosomal protein S16
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PEG10 paternally expressed 10
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ADAM9 ADAM metallopeptidase domain 9
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
BASP1 brain abundant, membrane attached signal protein 1
CA2 carbonic anhydrase II
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CTBP2 C-terminal binding protein 2
DFNA5 deafness, autosomal dominant 5
DUOX2 dual oxidase 2
FADS1 fatty acid desaturase 1
FZD2 frizzled class receptor 2
GAL galanin/GMAP prepropeptide
GBP1 guanylate binding protein 1, interferon-inducible
HACD1 3-hydroxyacyl-CoA dehydratase 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
KIAA1033 KIAA1033
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LITAF lipopolysaccharide-induced TNF factor
LOXL2 lysyl oxidase-like 2
MTCL1 microtubule crosslinking factor 1
PDZK1IP1 PDZK1 interacting protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKD2 polycystic kidney disease 2 (autosomal dominant)
PPARD peroxisome proliferator-activated receptor delta
RGS5 regulator of G-protein signaling 5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RTN2 reticulon 2
SLC38A1 solute carrier family 38, member 1
TPD52 tumor protein D52
VCAN versican
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1