BRD-K76969307_CG-930_PC3_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K76969307_CG-930_PC3_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
EMP1 epithelial membrane protein 1
FXYD3 FXYD domain containing ion transport regulator 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GPNMB glycoprotein (transmembrane) nmb
HEPH hephaestin
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
KIF5C kinesin family member 5C
LGALS4 lectin, galactoside-binding, soluble, 4
LXN latexin
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYO5C myosin VC
NELL2 NEL-like 2 (chicken)
NR2F2 nuclear receptor subfamily 2, group F, member 2
ORC1 origin recognition complex, subunit 1
OSBPL10 oxysterol binding protein-like 10
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDE4D phosphodiesterase 4D, cAMP-specific
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
SFRP1 secreted frizzled-related protein 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TNS3 tensin 3
TRAF3 TNF receptor-associated factor 3
XIST X inactive specific transcript (non-protein coding)
XPO7 exportin 7

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACTA2 actin, alpha 2, smooth muscle, aorta
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AQP3 aquaporin 3 (Gill blood group)
ARG1 arginase 1
CALML3 calmodulin-like 3
FLG filaggrin
FOLR1 folate receptor 1 (adult)
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
HIST1H2BG histone cluster 1, H2bg
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KIF14 kinesin family member 14
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MXRA7 matrix-remodelling associated 7
OXTR oxytocin receptor
RBP1 retinol binding protein 1, cellular
RHOB ras homolog family member B
S100A7 S100 calcium binding protein A7
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPRR1A small proline-rich protein 1A
TAGLN transgelin
TPSB2 tryptase beta 2 (gene/pseudogene)
ZIC1 Zic family member 1