BRD-K76969307_CG-930_HA1E_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K76969307_CG-930_HA1E_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
ALDOA aldolase A, fructose-bisphosphate
ASRGL1 asparaginase like 1
BCL6 B-cell CLL/lymphoma 6
CA2 carbonic anhydrase II
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DUT deoxyuridine triphosphatase
ESR1 estrogen receptor 1
FOLR1 folate receptor 1 (adult)
GNB5 guanine nucleotide binding protein (G protein), beta 5
IRF8 interferon regulatory factor 8
LGALS3 lectin, galactoside-binding, soluble, 3
LOC100505650 uncharacterized LOC100505650
MBP myelin basic protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRCAM neuronal cell adhesion molecule
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
RPL38 ribosomal protein L38
RUFY3 RUN and FYVE domain containing 3
SCGB2A2 secretoglobin, family 2A, member 2
SH3YL1 SH3 and SYLF domain containing 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TEX10 testis expressed 10
TFRC transferrin receptor
WSB1 WD repeat and SOCS box containing 1
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AXL AXL receptor tyrosine kinase
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
CCR7 chemokine (C-C motif) receptor 7
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC2B C-type lectin domain family 2, member B
COL4A5 collagen, type IV, alpha 5
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYTIP cytohesin 1 interacting protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5 eukaryotic translation initiation factor 5
EVI2B ecotropic viral integration site 2B
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FXYD3 FXYD domain containing ion transport regulator 3
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JCHAIN joining chain of multimeric IgA and IgM
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT81 keratin 81, type II
LAMB1 laminin, beta 1
LUM lumican
LYPLA1 lysophospholipase I
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MELK maternal embryonic leucine zipper kinase
MGP matrix Gla protein
MYH11 myosin, heavy chain 11, smooth muscle
PDE4B phosphodiesterase 4B, cAMP-specific
PLAT plasminogen activator, tissue
POSTN periostin, osteoblast specific factor
PTP4A1 protein tyrosine phosphatase type IVA, member 1
S100A7 S100 calcium binding protein A7
SOAT1 sterol O-acyltransferase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
TM4SF1 transmembrane 4 L six family member 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPM2 tropomyosin 2 (beta)
VEGFC vascular endothelial growth factor C