BRD-K76969307_CG-930_A375_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K76969307_CG-930_A375_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOA aldolase A, fructose-bisphosphate
CCND2 cyclin D2
CPNE1 copine I
CXADR coxsackie virus and adenovirus receptor
ETV1 ets variant 1
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
GSTA4 glutathione S-transferase alpha 4
IL13RA1 interleukin 13 receptor, alpha 1
LGALS4 lectin, galactoside-binding, soluble, 4
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MT1E metallothionein 1E
MTMR11 myotubularin related protein 11
MYL9 myosin, light chain 9, regulatory
NUPR1 nuclear protein, transcriptional regulator, 1
PBX3 pre-B-cell leukemia homeobox 3
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRR15L proline rich 15-like
RNASET2 ribonuclease T2
RTN2 reticulon 2
SCAND1 SCAN domain containing 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SOCS2 suppressor of cytokine signaling 2
SPAG4 sperm associated antigen 4
SPRED2 sprouty-related, EVH1 domain containing 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TPP1 tripeptidyl peptidase I
TRIM2 tripartite motif containing 2
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
BACE2 beta-site APP-cleaving enzyme 2
BPHL biphenyl hydrolase-like (serine hydrolase)
CALB1 calbindin 1, 28kDa
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCND1 cyclin D1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CST7 cystatin F (leukocystatin)
CTSZ cathepsin Z
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DCBLD2 discoidin, CUB and LCCL domain containing 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZR ezrin
FKBP11 FK506 binding protein 11, 19 kDa
FOSL1 FOS-like antigen 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLS glutaminase
GRWD1 glutamate-rich WD repeat containing 1
HES1 hes family bHLH transcription factor 1
HIST2H2BE histone cluster 2, H2be
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPH1 heat shock 105kDa/110kDa protein 1
IGHM immunoglobulin heavy constant mu
IL13RA2 interleukin 13 receptor, alpha 2
KRT5 keratin 5, type II
LAMB1 laminin, beta 1
MAL mal, T-cell differentiation protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSH6 mutS homolog 6
ODC1 ornithine decarboxylase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRPF4 pre-mRNA processing factor 4
PTBP3 polypyrimidine tract binding protein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A2 S100 calcium binding protein A2
TEX10 testis expressed 10
TPM4 tropomyosin 4
ZFP36L1 ZFP36 ring finger protein-like 1