BRD-K76951091_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K76951091_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
ATF3 activating transcription factor 3
BTG3 BTG family, member 3
C10ORF10 chromosome 10 open reading frame 10
C3ORF14 chromosome 3 open reading frame 14
CA12 carbonic anhydrase XII
CD200 CD200 molecule
CLIC5 chloride intracellular channel 5
CXCL10 chemokine (C-X-C motif) ligand 10
DOK5 docking protein 5
EPN2 epsin 2
FBXL12 F-box and leucine-rich repeat protein 12
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GEM GTP binding protein overexpressed in skeletal muscle
GSPT2 G1 to S phase transition 2
HOXB2 homeobox B2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LDOC1 leucine zipper, down-regulated in cancer 1
MT1E metallothionein 1E
MT1F metallothionein 1F
NANOG Nanog homeobox
NPTX2 neuronal pentraxin II
PDGFC platelet derived growth factor C
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRL platelet-derived growth factor receptor-like
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PRUNE2 prune homolog 2 (Drosophila)
PTPRK protein tyrosine phosphatase, receptor type, K
RAB31 RAB31, member RAS oncogene family
RBPMS RNA binding protein with multiple splicing
RLN2 relaxin 2
SCG5 secretogranin V
SCN3A sodium channel, voltage gated, type III alpha subunit
SPON1 spondin 1, extracellular matrix protein
TCF4 transcription factor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TUSC3 tumor suppressor candidate 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AUTS2 autism susceptibility candidate 2
C2CD2 C2 calcium-dependent domain containing 2
CPD carboxypeptidase D
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F3 coagulation factor III (thromboplastin, tissue factor)
FOLR1 folate receptor 1 (adult)
GMDS GDP-mannose 4,6-dehydratase
H2AFV H2A histone family, member V
IL6ST interleukin 6 signal transducer
KRT17 keratin 17, type I
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LRRC16A leucine rich repeat containing 16A
MKNK2 MAP kinase interacting serine/threonine kinase 2
MTUS1 microtubule associated tumor suppressor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NKX3-1 NK3 homeobox 1
NRN1 neuritin 1
PLAC8 placenta-specific 8
PXMP2 peroxisomal membrane protein 2, 22kDa
RAD23B RAD23 homolog B (S. cerevisiae)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNF167 ring finger protein 167
RPS11 ribosomal protein S11
SIDT2 SID1 transmembrane family, member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SRSF6 serine/arginine-rich splicing factor 6
SVIL supervillin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TTC3 tetratricopeptide repeat domain 3
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein