BRD-K76595177_1-[2-(2,5-dimethylphenoxy)ethyl]-1H-indole-3-carboxylic acid_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K76595177_1-[2-(2,5-dimethylphenoxy)ethyl]-1H-indole-3-carboxylic acid_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
BID BH3 interacting domain death agonist
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLIC4 chloride intracellular channel 4
COCH cochlin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FPGS folylpolyglutamate synthase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAS1 growth arrest-specific 1
HMOX1 heme oxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
IL1B interleukin 1, beta
KAZN kazrin, periplakin interacting protein
KLF4 Kruppel-like factor 4 (gut)
MAPT microtubule-associated protein tau
MSMB microseminoprotein, beta-
NKX3-1 NK3 homeobox 1
NPY1R neuropeptide Y receptor Y1
RTN2 reticulon 2
STK26 serine/threonine protein kinase 26
TNS1 tensin 1
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
DHRS2 dehydrogenase/reductase (SDR family) member 2
FABP7 fatty acid binding protein 7, brain
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FXYD5 FXYD domain containing ion transport regulator 5
HTRA1 HtrA serine peptidase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LAPTM4B lysosomal protein transmembrane 4 beta
MBP myelin basic protein
NRP1 neuropilin 1
POSTN periostin, osteoblast specific factor
SKP1 S-phase kinase-associated protein 1