BRD-K76211160_4-Fluoro-N-pyridin-3-yl-benzamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K76211160_4-Fluoro-N-pyridin-3-yl-benzamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AURKB aurora kinase B
CD200 CD200 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHEK1 checkpoint kinase 1
COL4A1 collagen, type IV, alpha 1
CPE carboxypeptidase E
CX3CR1 chemokine (C-X3-C motif) receptor 1
ESM1 endothelial cell-specific molecule 1
KRT20 keratin 20, type I
LRRC15 leucine rich repeat containing 15
MMP2 matrix metallopeptidase 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
SULF1 sulfatase 1

decreased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AQP3 aquaporin 3 (Gill blood group)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
C6ORF48 chromosome 6 open reading frame 48
CHIC2 cysteine-rich hydrophobic domain 2
CHPT1 choline phosphotransferase 1
CPM carboxypeptidase M
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP10 dual specificity phosphatase 10
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLC glutamate-cysteine ligase, catalytic subunit
GHR growth hormone receptor
GLRX glutaredoxin (thioltransferase)
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
IGFBP6 insulin-like growth factor binding protein 6
KYNU kynureninase
MCOLN1 mucolipin 1
NPY neuropeptide Y
NUP98 nucleoporin 98kDa
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PROM1 prominin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
STOM stomatin
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1