BRD-K76211160_4-Fluoro-N-pyridin-3-yl-benzamide_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K76211160_4-Fluoro-N-pyridin-3-yl-benzamide_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CD163 CD163 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F13A1 coagulation factor XIII, A1 polypeptide
HSPA1A heat shock 70kDa protein 1A
KRT19 keratin 19, type I
MAGEA3 melanoma antigen family A3
MAOA monoamine oxidase A
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MT1X metallothionein 1X
NFIB nuclear factor I/B
NNMT nicotinamide N-methyltransferase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RGS16 regulator of G-protein signaling 16
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC1 syndecan 1
SFN stratifin
SPON2 spondin 2, extracellular matrix protein
STK26 serine/threonine protein kinase 26
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM45A transmembrane protein 45A
VGLL4 vestigial-like family member 4
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AP2B1 adaptor-related protein complex 2, beta 1 subunit
BCL6 B-cell CLL/lymphoma 6
C6ORF62 chromosome 6 open reading frame 62
CALD1 caldesmon 1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CDC42 cell division cycle 42
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLU clusterin
CNN2 calponin 2
CNN3 calponin 3, acidic
COL6A1 collagen, type VI, alpha 1
CTNND1 catenin (cadherin-associated protein), delta 1
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FERMT2 fermitin family member 2
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
GAS1 growth arrest-specific 1
GDI2 GDP dissociation inhibitor 2
GLS glutaminase
GPC3 glypican 3
IGFBP5 insulin-like growth factor binding protein 5
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCTD12 potassium channel tetramerization domain containing 12
LIMA1 LIM domain and actin binding 1
LOX lysyl oxidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
PEA15 phosphoprotein enriched in astrocytes 15
PFKP phosphofructokinase, platelet
RAD23B RAD23 homolog B (S. cerevisiae)
RGCC regulator of cell cycle
SELL selectin L
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
STC2 stanniocalcin 2
TFRC transferrin receptor
XIST X inactive specific transcript (non-protein coding)
ZFP36L1 ZFP36 ring finger protein-like 1