BRD-K76211160_4-Fluoro-N-pyridin-3-yl-benzamide_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K76211160_4-Fluoro-N-pyridin-3-yl-benzamide_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADIRF adipogenesis regulatory factor
APOLD1 apolipoprotein L domain containing 1
ASS1 argininosuccinate synthase 1
CCND2 cyclin D2
CD24 CD24 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKB creatine kinase, brain
CLU clusterin
CPA3 carboxypeptidase A3 (mast cell)
CPM carboxypeptidase M
DCLK1 doublecortin-like kinase 1
EPAS1 endothelial PAS domain protein 1
GPM6B glycoprotein M6B
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMGB3 high mobility group box 3
IGF1 insulin-like growth factor 1 (somatomedin C)
MAN1A1 mannosidase, alpha, class 1A, member 1
MT1M metallothionein 1M
MTSS1 metastasis suppressor 1
PALMD palmdelphin
PBX1 pre-B-cell leukemia homeobox 1
PDGFC platelet derived growth factor C
PFN2 profilin 2
PTN pleiotrophin
RBP1 retinol binding protein 1, cellular
TARP TCR gamma alternate reading frame protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TMSB15A thymosin beta 15a
TP53I3 tumor protein p53 inducible protein 3
TPGS2 tubulin polyglutamylase complex subunit 2

decreased expression

Symbol Name
AIM2 absent in melanoma 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BCL2A1 BCL2-related protein A1
BST2 bone marrow stromal cell antigen 2
CCND1 cyclin D1
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEMIP cell migration inducing protein, hyaluronan binding
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLX2 distal-less homeobox 2
HBB hemoglobin, beta
HLA-DRA major histocompatibility complex, class II, DR alpha
IFI16 interferon, gamma-inducible protein 16
INHBA inhibin, beta A
MAPT microtubule-associated protein tau
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PLAT plasminogen activator, tissue
S100A8 S100 calcium binding protein A8
SDC2 syndecan 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC43A3 solute carrier family 43, member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
THBS2 thrombospondin 2
TPM4 tropomyosin 4
XIST X inactive specific transcript (non-protein coding)