BRD-K76018977_Cefotaxime sodium salt_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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59 genes differentially expressed following the BRD-K76018977_Cefotaxime sodium salt_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASS1 argininosuccinate synthase 1
BASP1 brain abundant, membrane attached signal protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EZR ezrin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GPATCH8 G patch domain containing 8
GSTT1 glutathione S-transferase theta 1
IFITM1 interferon induced transmembrane protein 1
IGFBP4 insulin-like growth factor binding protein 4
KDM5D lysine (K)-specific demethylase 5D
KIAA0100 KIAA0100
LASP1 LIM and SH3 protein 1
LOC100505650 uncharacterized LOC100505650
MRPS16 mitochondrial ribosomal protein S16
PCGF2 polycomb group ring finger 2
PFKP phosphofructokinase, platelet
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SKP1 S-phase kinase-associated protein 1
TFF1 trefoil factor 1
VNN1 vanin 1

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
ARL4C ADP-ribosylation factor-like 4C
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
CA2 carbonic anhydrase II
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CNN3 calponin 3, acidic
CPB1 carboxypeptidase B1 (tissue)
CPOX coproporphyrinogen oxidase
CYCS cytochrome c, somatic
DST dystonin
EIF5A eukaryotic translation initiation factor 5A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GSPT2 G1 to S phase transition 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT15 keratin 15, type I
LUM lumican
MTSS1 metastasis suppressor 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PRUNE2 prune homolog 2 (Drosophila)
PSPH phosphoserine phosphatase
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REEP1 receptor accessory protein 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SMC1A structural maintenance of chromosomes 1A
SQLE squalene epoxidase
TES testin LIM domain protein
TMEM70 transmembrane protein 70
VEGFA vascular endothelial growth factor A