BRD-K74931283_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K74931283_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL20 chemokine (C-C motif) ligand 20
CLDN3 claudin 3
COBL cordon-bleu WH2 repeat protein
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
HEPH hephaestin
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
JCHAIN joining chain of multimeric IgA and IgM
MLF1 myeloid leukemia factor 1
PENK proenkephalin
POSTN periostin, osteoblast specific factor
PTPRD protein tyrosine phosphatase, receptor type, D
STC2 stanniocalcin 2
TFF1 trefoil factor 1
TMEM110 transmembrane protein 110
VCAM1 vascular cell adhesion molecule 1
XYLT1 xylosyltransferase I
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
OBSL1 obscurin-like 1
RBMS1 RNA binding motif, single stranded interacting protein 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SOX4 SRY (sex determining region Y)-box 4
TGFB1 transforming growth factor, beta 1
TKT transketolase
TMEM45A transmembrane protein 45A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10