BRD-K73437736_Azlocillin sodium salt_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K73437736_Azlocillin sodium salt_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
AK1 adenylate kinase 1
ANXA3 annexin A3
ANXA5 annexin A5
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CD59 CD59 molecule, complement regulatory protein
COCH cochlin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
HOXC6 homeobox C6
IGFBP6 insulin-like growth factor binding protein 6
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KRT14 keratin 14, type I
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NFIB nuclear factor I/B
NPY neuropeptide Y
PLS3 plastin 3
PRDX2 peroxiredoxin 2
PRSS3 protease, serine, 3
RBP4 retinol binding protein 4, plasma
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPS26 ribosomal protein S26
S100A2 S100 calcium binding protein A2
SCML1 sex comb on midleg-like 1 (Drosophila)
SIRT3 sirtuin 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORD sorbitol dehydrogenase
STXBP2 syntaxin binding protein 2
TBC1D4 TBC1 domain family, member 4
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRL2 adhesion G protein-coupled receptor L2
AKAP12 A kinase (PRKA) anchor protein 12
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CADM1 cell adhesion molecule 1
CLEC2B C-type lectin domain family 2, member B
CPE carboxypeptidase E
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHRS2 dehydrogenase/reductase (SDR family) member 2
EGFL6 EGF-like-domain, multiple 6
EGR1 early growth response 1
ELANE elastase, neutrophil expressed
ERBB4 erb-b2 receptor tyrosine kinase 4
EZR ezrin
GRB7 growth factor receptor-bound protein 7
HBE1 hemoglobin, epsilon 1
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
MMP2 matrix metallopeptidase 2
MX1 MX dynamin-like GTPase 1
NCAM1 neural cell adhesion molecule 1
NRCAM neuronal cell adhesion molecule
NREP neuronal regeneration related protein
PEG10 paternally expressed 10
PMM2 phosphomannomutase 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCARB2 scavenger receptor class B, member 2
SPARCL1 SPARC-like 1 (hevin)
SUSD4 sushi domain containing 4
TMSB15A thymosin beta 15a
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)
ZNF91 zinc finger protein 91