BRD-K73368362_BIX-02189_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K73368362_BIX-02189_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIPOQ adiponectin, C1Q and collagen domain containing
AIM2 absent in melanoma 2
BAG2 BCL2-associated athanogene 2
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CFLAR CASP8 and FADD-like apoptosis regulator
CKB creatine kinase, brain
CLC Charcot-Leyden crystal galectin
CLGN calmegin
COBL cordon-bleu WH2 repeat protein
CREB1 cAMP responsive element binding protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
GDF15 growth differentiation factor 15
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPX1 glutathione peroxidase 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IDO1 indoleamine 2,3-dioxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KDM5D lysine (K)-specific demethylase 5D
LAMP3 lysosomal-associated membrane protein 3
LXN latexin
MAOA monoamine oxidase A
MID1 midline 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
PLCB4 phospholipase C, beta 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PXMP2 peroxisomal membrane protein 2, 22kDa
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SFRP1 secreted frizzled-related protein 1
SHOX2 short stature homeobox 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STAT1 signal transducer and activator of transcription 1, 91kDa
TBC1D31 TBC1 domain family, member 31
THBS1 thrombospondin 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
BHLHE40 basic helix-loop-helix family, member e40
C6ORF62 chromosome 6 open reading frame 62
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLTB clathrin, light chain B
CTSB cathepsin B
CTSO cathepsin O
DCN decorin
FDFT1 farnesyl-diphosphate farnesyltransferase 1
IPO13 importin 13
LYZ lysozyme
MEOX2 mesenchyme homeobox 2
MT1M metallothionein 1M
NDRG1 N-myc downstream regulated 1
NPTX2 neuronal pentraxin II
PDGFC platelet derived growth factor C
PDIA3 protein disulfide isomerase family A, member 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
TAGLN2 transgelin 2
TM4SF1 transmembrane 4 L six family member 1
TM9SF3 transmembrane 9 superfamily member 3
TMEM70 transmembrane protein 70
XIST X inactive specific transcript (non-protein coding)
YME1L1 YME1-like 1 ATPase
ZFP36L2 ZFP36 ring finger protein-like 2