BRD-K73319509_-666_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K73319509_-666_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
AKR1C2 aldo-keto reductase family 1, member C2
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ARG2 arginase 2
ARHGAP29 Rho GTPase activating protein 29
ARMCX1 armadillo repeat containing, X-linked 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CALD1 caldesmon 1
CD36 CD36 molecule (thrombospondin receptor)
CHRDL1 chordin-like 1
CLGN calmegin
CNPY3 canopy FGF signaling regulator 3
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
EDNRB endothelin receptor type B
ELOVL5 ELOVL fatty acid elongase 5
FGF13 fibroblast growth factor 13
FGFR2 fibroblast growth factor receptor 2
GCLC glutamate-cysteine ligase, catalytic subunit
GLRX glutaredoxin (thioltransferase)
HMGA1 high mobility group AT-hook 1
HSPG2 heparan sulfate proteoglycan 2
INHBB inhibin, beta B
JAG1 jagged 1
KLK3 kallikrein-related peptidase 3
LPAR6 lysophosphatidic acid receptor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MME membrane metallo-endopeptidase
MTSS1 metastasis suppressor 1
MYOF myoferlin
NELL2 NEL-like 2 (chicken)
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLIN2 perilipin 2
PRAME preferentially expressed antigen in melanoma
PTPRO protein tyrosine phosphatase, receptor type, O
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
RND3 Rho family GTPase 3
S100A8 S100 calcium binding protein A8
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC38A2 solute carrier family 38, member 2
SRGN serglycin
ST18 suppression of tumorigenicity 18, zinc finger
STEAP1 six transmembrane epithelial antigen of the prostate 1
TACSTD2 tumor-associated calcium signal transducer 2
TRD T cell receptor delta locus
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
ACTA2 actin, alpha 2, smooth muscle, aorta
ARPC5L actin related protein 2/3 complex, subunit 5-like
BEX1 brain expressed, X-linked 1
BLM Bloom syndrome, RecQ helicase-like
BST2 bone marrow stromal cell antigen 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CRIP1 cysteine-rich protein 1 (intestinal)
GPX1 glutathione peroxidase 1
IFI27 interferon, alpha-inducible protein 27
LDLR low density lipoprotein receptor
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MARCKS myristoylated alanine-rich protein kinase C substrate
MGLL monoglyceride lipase
MRPS30 mitochondrial ribosomal protein S30
MT1E metallothionein 1E
MT1X metallothionein 1X
NGRN neugrin, neurite outgrowth associated
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAT plasminogen activator, tissue
PNMA1 paraneoplastic Ma antigen 1
PNMA2 paraneoplastic Ma antigen 2
RALGDS ral guanine nucleotide dissociation stimulator
RGS13 regulator of G-protein signaling 13
RPL36 ribosomal protein L36
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC35F2 solute carrier family 35, member F2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBC1D4 TBC1 domain family, member 4
TFF3 trefoil factor 3 (intestinal)
THY1 Thy-1 cell surface antigen
TUBB4B tubulin, beta 4B class IVb
UBE3B ubiquitin protein ligase E3B