BRD-K73319509_-666_SW620_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K73319509_-666_SW620_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BIRC3 baculoviral IAP repeat containing 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CRYZ crystallin, zeta (quinone reductase)
DPP4 dipeptidyl-peptidase 4
ENO1 enolase 1, (alpha)
F2RL1 coagulation factor II (thrombin) receptor-like 1
HOXB7 homeobox B7
ICAM2 intercellular adhesion molecule 2
IFI27 interferon, alpha-inducible protein 27
KLF4 Kruppel-like factor 4 (gut)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS4 lectin, galactoside-binding, soluble, 4
LIMA1 LIM domain and actin binding 1
MICB MHC class I polypeptide-related sequence B
MMD monocyte to macrophage differentiation-associated
MYH10 myosin, heavy chain 10, non-muscle
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PLAGL1 pleiomorphic adenoma gene-like 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRSS2 protease, serine, 2 (trypsin 2)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RALB v-ral simian leukemia viral oncogene homolog B
RCAN2 regulator of calcineurin 2
RTN1 reticulon 1
SDPR serum deprivation response
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGK1 serum/glucocorticoid regulated kinase 1
TSPAN8 tetraspanin 8
UBE2A ubiquitin-conjugating enzyme E2A
UBE2E3 ubiquitin-conjugating enzyme E2E 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ASCL1 achaete-scute family bHLH transcription factor 1
DPYSL3 dihydropyrimidinase-like 3
FOLR1 folate receptor 1 (adult)
HIRA histone cell cycle regulator
HIST1H2BG histone cluster 1, H2bg
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL7R interleukin 7 receptor
LBH limb bud and heart development
LOX lysyl oxidase
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
NKX3-1 NK3 homeobox 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
PMP22 peripheral myelin protein 22
RFC5 replication factor C (activator 1) 5, 36.5kDa
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORD sorbitol dehydrogenase
SULF1 sulfatase 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNNT1 troponin T type 1 (skeletal, slow)
TUSC3 tumor suppressor candidate 3
UGDH UDP-glucose 6-dehydrogenase
XYLT1 xylosyltransferase I