BRD-K73319509_-666_RMUGS_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K73319509_-666_RMUGS_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF5 activating transcription factor 5
C8ORF4 chromosome 8 open reading frame 4
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKS2 CDC28 protein kinase regulatory subunit 2
CPVL carboxypeptidase, vitellogenic-like
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
ELOVL2 ELOVL fatty acid elongase 2
GDF15 growth differentiation factor 15
GPX7 glutathione peroxidase 7
HOXC6 homeobox C6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM2 interferon induced transmembrane protein 2
JMJD6 jumonji domain containing 6
LAT2 linker for activation of T cells family, member 2
LMO2 LIM domain only 2 (rhombotin-like 1)
PLA2G16 phospholipase A2, group XVI
PLK2 polo-like kinase 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTMA prothymosin, alpha
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOBTB3 Rho-related BTB domain containing 3
RPA3 replication protein A3, 14kDa
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TACC3 transforming, acidic coiled-coil containing protein 3
TESC tescalcin
TOB1 transducer of ERBB2, 1
TSC22D2 TSC22 domain family, member 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CAV1 caveolin 1, caveolae protein, 22kDa
CLCA1 chloride channel accessory 1
COG7 component of oligomeric golgi complex 7
COL7A1 collagen, type VII, alpha 1
COL9A2 collagen, type IX, alpha 2
CORO1A coronin, actin binding protein, 1A
CSTA cystatin A (stefin A)
CXCL10 chemokine (C-X-C motif) ligand 10
DENND1B DENN/MADD domain containing 1B
DSP desmoplakin
DST dystonin
FABP4 fatty acid binding protein 4, adipocyte
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
GJA1 gap junction protein, alpha 1, 43kDa
GRB7 growth factor receptor-bound protein 7
GSDMB gasdermin B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGKC immunoglobulin kappa constant
INA internexin neuronal intermediate filament protein, alpha
IRF6 interferon regulatory factor 6
JAG1 jagged 1
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
LMOD1 leiomodin 1 (smooth muscle)
MLPH melanophilin
MSMB microseminoprotein, beta-
MTSS1 metastasis suppressor 1
NARFL nuclear prelamin A recognition factor-like
NDRG1 N-myc downstream regulated 1
NVL nuclear VCP-like
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PPAP2B phosphatidic acid phosphatase type 2B
PTHLH parathyroid hormone-like hormone
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNASE4 ribonuclease, RNase A family, 4
RTN1 reticulon 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SHB Src homology 2 domain containing adaptor protein B
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPARCL1 SPARC-like 1 (hevin)
TSPAN7 tetraspanin 7
VEGFA vascular endothelial growth factor A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WFDC1 WAP four-disulfide core domain 1
ZNF395 zinc finger protein 395