BRD-K73319509_-666_MDST8_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

105 genes differentially expressed following the BRD-K73319509_-666_MDST8_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADA adenosine deaminase
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG1 adhesion G protein-coupled receptor G1
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD36B ankyrin repeat domain 36B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG3 BTG family, member 3
CA2 carbonic anhydrase II
CCND2 cyclin D2
CD8A CD8a molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNPY3 canopy FGF signaling regulator 3
CRABP2 cellular retinoic acid binding protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFHD1 EF-hand domain family, member D1
GATA3 GATA binding protein 3
GLO1 glyoxalase I
GNLY granulysin
GPM6B glycoprotein M6B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGL immunoglobulin lambda locus
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LAMP3 lysosomal-associated membrane protein 3
LRRC15 leucine rich repeat containing 15
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MCOLN1 mucolipin 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NTS neurotensin
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
QPCT glutaminyl-peptide cyclotransferase
RAI14 retinoic acid induced 14
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SDC1 syndecan 1
SEPP1 selenoprotein P, plasma, 1
SKP1 S-phase kinase-associated protein 1
SNX13 sorting nexin 13
SPRED2 sprouty-related, EVH1 domain containing 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TMEM45A transmembrane protein 45A
TPD52 tumor protein D52
TSPAN13 tetraspanin 13
VEGFA vascular endothelial growth factor A
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ASRGL1 asparaginase like 1
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BIN1 bridging integrator 1
C1R complement component 1, r subcomponent
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
CLEC2B C-type lectin domain family 2, member B
CST3 cystatin C
CYTL1 cytokine-like 1
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
ENO1 enolase 1, (alpha)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46A family with sequence similarity 46, member A
FLNA filamin A, alpha
FOLR1 folate receptor 1 (adult)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IRS2 insulin receptor substrate 2
MMP7 matrix metallopeptidase 7
MTCL1 microtubule crosslinking factor 1
NQO1 NAD(P)H dehydrogenase, quinone 1
ODC1 ornithine decarboxylase 1
PDLIM4 PDZ and LIM domain 4
PKM pyruvate kinase, muscle
PLTP phospholipid transfer protein
PRR7 proline rich 7 (synaptic)
RELN reelin
S100A2 S100 calcium binding protein A2
SCGB2A1 secretoglobin, family 2A, member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TAGLN2 transgelin 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
WFDC2 WAP four-disulfide core domain 2
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZCCHC24 zinc finger, CCHC domain containing 24