BRD-K73319509_-666_HEPG2_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K73319509_-666_HEPG2_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
BMP4 bone morphogenetic protein 4
CA2 carbonic anhydrase II
CAPN2 calpain 2, (m/II) large subunit
CCR2 chemokine (C-C motif) receptor 2
CLIC5 chloride intracellular channel 5
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EGFL6 EGF-like-domain, multiple 6
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FMO3 flavin containing monooxygenase 3
FRY furry homolog (Drosophila)
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GATA6 GATA binding protein 6
GREM1 gremlin 1, DAN family BMP antagonist
GSTA1 glutathione S-transferase alpha 1
HIST1H1C histone cluster 1, H1c
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL13RA1 interleukin 13 receptor, alpha 1
IPO13 importin 13
LPAR6 lysophosphatidic acid receptor 6
MTSS1 metastasis suppressor 1
MYO1D myosin ID
NEB nebulin
NMU neuromedin U
ORC1 origin recognition complex, subunit 1
PPOX protoporphyrinogen oxidase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
RRM2 ribonucleotide reductase M2
SHB Src homology 2 domain containing adaptor protein B
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SULF1 sulfatase 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ANXA3 annexin A3
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
CALD1 caldesmon 1
CD24 CD24 molecule
CDC42 cell division cycle 42
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSRP1 cysteine and glycine-rich protein 1
CXCL14 chemokine (C-X-C motif) ligand 14
DLD dihydrolipoamide dehydrogenase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GPM6B glycoprotein M6B
LAPTM4B lysosomal protein transmembrane 4 beta
LAPTM5 lysosomal protein transmembrane 5
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
NFIB nuclear factor I/B
NR1D2 nuclear receptor subfamily 1, group D, member 2
PEBP1 phosphatidylethanolamine binding protein 1
PLAT plasminogen activator, tissue
PON2 paraoxonase 2
PSAT1 phosphoserine aminotransferase 1
RNASET2 ribonuclease T2
SCRG1 stimulator of chondrogenesis 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLPI secretory leukocyte peptidase inhibitor
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)