BRD-K72541103_JAK3 Inhibitor I_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

14 genes differentially expressed following the BRD-K72541103_JAK3 Inhibitor I_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLC glutamate-cysteine ligase, catalytic subunit

decreased expression

Symbol Name
CD24 CD24 molecule
CFD complement factor D (adipsin)
CFH complement factor H
CRISP3 cysteine-rich secretory protein 3
CYCS cytochrome c, somatic
DEFB1 defensin, beta 1
ICAM3 intercellular adhesion molecule 3
IGFBP3 insulin-like growth factor binding protein 3
IL7R interleukin 7 receptor
INHBA inhibin, beta A
PCOLCE2 procollagen C-endopeptidase enhancer 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Funding