| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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87 genes differentially expressed following the BRD-K72541103_JAK3 Inhibitor I_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADAMDEC1 | ADAM-like, decysin 1 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AHR | aryl hydrocarbon receptor |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| CADM1 | cell adhesion molecule 1 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| COL4A5 | collagen, type IV, alpha 5 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| FRY | furry homolog (Drosophila) |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GIMAP4 | GTPase, IMAP family member 4 |
| GSTT1 | glutathione S-transferase theta 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KDR | kinase insert domain receptor |
| LDB2 | LIM domain binding 2 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LOC100505650 | uncharacterized LOC100505650 |
| MNDA | myeloid cell nuclear differentiation antigen |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| OPN3 | opsin 3 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PMM2 | phosphomannomutase 2 |
| PRTN3 | proteinase 3 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RCAN2 | regulator of calcineurin 2 |
| RGS5 | regulator of G-protein signaling 5 |
| SEPP1 | selenoprotein P, plasma, 1 |
| TFEC | transcription factor EC |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| WT1 | Wilms tumor 1 |
| Symbol | Name |
|---|---|
| AK4 | adenylate kinase 4 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| APOD | apolipoprotein D |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DEFB1 | defensin, beta 1 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
| DUSP5 | dual specificity phosphatase 5 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF5A | eukaryotic translation initiation factor 5A |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| GOLGA8A | golgin A8 family, member A |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOMER1 | homer scaffolding protein 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KRT23 | keratin 23, type I |
| LDLR | low density lipoprotein receptor |
| LRRC16A | leucine rich repeat containing 16A |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MOK | MOK protein kinase |
| MT1E | metallothionein 1E |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1X | metallothionein 1X |
| NRIP3 | nuclear receptor interacting protein 3 |
| OXTR | oxytocin receptor |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLP1 | proteolipid protein 1 |
| RCAN1 | regulator of calcineurin 1 |
| RRAGD | Ras-related GTP binding D |
| S100A2 | S100 calcium binding protein A2 |
| S100B | S100 calcium binding protein B |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SET | SET nuclear proto-oncogene |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| ZC3H15 | zinc finger CCCH-type containing 15 |
