BRD-K72420232_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K72420232_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
APOD apolipoprotein D
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMCX1 armadillo repeat containing, X-linked 1
CD163 CD163 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLCA2 chloride channel accessory 2
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DHRS3 dehydrogenase/reductase (SDR family) member 3
EMX2 empty spiracles homeobox 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB3 erb-b2 receptor tyrosine kinase 3
FGFR1 fibroblast growth factor receptor 1
GAA glucosidase, alpha; acid
GRB14 growth factor receptor-bound protein 14
GRN granulin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
IGF1R insulin-like growth factor 1 receptor
KRT6A keratin 6A, type II
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MFAP5 microfibrillar associated protein 5
MYO10 myosin X
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
RAB38 RAB38, member RAS oncogene family
RBP1 retinol binding protein 1, cellular
TBL1X transducin (beta)-like 1X-linked
THBD thrombomodulin
TP53 tumor protein p53

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADD3 adducin 3 (gamma)
ANXA1 annexin A1
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
COX11 COX11 cytochrome c oxidase copper chaperone
DPYSL3 dihydropyrimidinase-like 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
IER3 immediate early response 3
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTBP1 latent transforming growth factor beta binding protein 1
MMP9 matrix metallopeptidase 9
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
ODC1 ornithine decarboxylase 1
PNP purine nucleoside phosphorylase
RBP4 retinol binding protein 4, plasma
RRM2 ribonucleotide reductase M2
S100A10 S100 calcium binding protein A10
SOX4 SRY (sex determining region Y)-box 4
TACSTD2 tumor-associated calcium signal transducer 2
TFRC transferrin receptor
TMEM158 transmembrane protein 158 (gene/pseudogene)